Test Name:
RUNX1::RUNX1T1 (AML1-ETO) t(8;21)
CPT Code:
81334
Turn Around Time:
24 – 72 hours
Clinical Application:
Detection and quantitative monitoring of the RUNX::RUNX1T 1 (AML::ETO) fusion transcripts, which are the molecular result of the t(8;21) translocation, associated with favorable prognosis in AML
Diagnosis and monitoring.
Methodology:
Real-Time Quantitative PCR, minimum sensitivity: 0.001%
AML1 exon5 – ETO Exon2
Specimen Requirements:
RNA-based assays
Peripheral Blood: Minimum 2 mL in EDTA (purple top) preferred or 2 mL in sodium heparin (green top)
Bone Marrow: Minimum 2 mL in EDTA (purple top) preferred or 2 mL in sodium heparin (green top)
Storage and Transportation:
Please store and ship specimens at ambient temperatures.
Ship RNA-based assays within 24 hours for optimal results.
Please refer to our full specimen requirements at Hematologics/Specimen Requirements for additional information and for directions on the storage and shipping of extracted DNA or RNA.