KIT D816V Mutation Analysis
Allele-specific PCR detection of the KIT D816V mutation in core-binding factor AML and mastocytosis.
TCF3::PBX1 (E2A::PBX1) t(1;19)
Quantitative RT-PCR detection of TCF3::PBX1 (E2A::PBX1) fusion from t(1;19) for ALL diagnosis and minimal residual disease monitoring.
B-Cell IGH Gene Rearrangement
PCR fragment-length analysis detecting clonal IGH rearrangements (FR1, FR2, FR3) for B-cell lymphoma diagnosis and monitoring.
KMT2A::MLLT3 (MLL::AF9) t(9;11)
Quantitative RT-PCR detection of KMT2A::MLLT3 fusion transcripts from the t(9;11) translocation.
NPM1 Mutation Analysis
PCR fragment analysis of common 4 bp insertion mutations in NPM1 exon 12 for AML diagnosis.
WT1 Gene Transcript Levels by RT-PCR
Quantitative RT-PCR determination of Wilms' Tumor (WT1) transcript levels for MDS and AML monitoring.
JAK2 Exon 12 Mutation Analysis
PCR fragment analysis of JAK2 exon 12 insertion/deletion and K539L mutations for myeloproliferative neoplasm diagnosis.
PML::RARA t(15;17)
Multiplex RT-PCR detection of PML::RARA fusion transcripts (long, variant, short isoforms) for acute promyelocytic leukemia diagnosis and monitoring. STAT testing available.
KMT2A::AFDN t(6;11) (aka KMT2A::MLLT4 or MLL::AF6)
Quantitative RT-PCR detection of KMT2A::AFDN fusion transcripts from t(6;11) involving the 11q23 KMT2A locus.
BRAF V600E Mutation Analysis
Sanger sequencing detection of the BRAF V600E mutation for hairy cell leukemia diagnosis and monitoring.
