WT1 Gene Transcript Levels by RT-PCR
Quantitative RT-PCR determination of Wilms' Tumor (WT1) transcript levels for MDS and AML monitoring.
KMT2A::MLLT10 (MLL::AF10) t(10;11)
Quantitative RQ-PCR detection of KMT2A::MLLT10 fusion transcripts from the t(10;11) translocation.
KMT2A::MLLT11 (MLL::AF1) t(1;11)
Quantitative RQ-PCR detection of KMT2A::MLLT11 fusion transcripts from the t(1;11) translocation.
KMT2A::MLLT3 (MLL::AF9) t(9;11)
Quantitative RQ-PCR detection of KMT2A::MLLT3 fusion transcripts from the t(9;11) translocation.
MYD88 L265P Mutation Analysis
Allele-specific PCR detection of MYD88 L265P mutation in lymphoplasmacytic lymphoma and Waldenström's macroglobulinemia.
KMT2A::MLLT1 / KMT2A::ELL t(11;19)
Quantitative RQ-PCR detection of KMT2A::MLLT1 (MLL::ENL) and KMT2A::ELL (MLL::ELL) fusion transcripts from t(11;19) in ALL and AML.
NPM1 Mutation Analysis
PCR fragment analysis of common 4 bp insertion mutations in NPM1 exon 12 for AML diagnosis.
NUP98::KDM5A t(11;12)
Quantitative RQ-PCR detection of NUP98::KDM5A fusion transcripts from the t(11;12)(p15;p13) translocation.
NUP98::NSD1 t(5;11)
Quantitative RQ-PCR detection of NUP98::NSD1 fusion transcripts from the cryptic t(5;11) translocation.
PML::RARA t(15;17)
Multiplex RQ-PCR detection of PML::RARA fusion transcripts (long, variant, short isoforms) for acute promyelocytic leukemia diagnosis and monitoring. STAT testing available.