WT1 Gene Transcript Levels by RT-PCR
Quantitative RT-PCR determination of Wilms' Tumor (WT1) transcript levels for MDS and AML monitoring.
JAK2 V617F Mutation Analysis
Allele-specific PCR detection of the JAK2 V617F mutation for myeloproliferative neoplasm diagnosis and monitoring.
STAT3 Mutation Analysis
Sanger sequencing of STAT3 exons 19, 20, and 21 mutations for T-LGL leukemia diagnosis. Cell sorting available for increased sensitivity.
KAT6A::CREBBP t(8;16)
Quantitative RQ-PCR detection of the KAT6A::CREBBP fusion from t(8;16)(p11;p13) translocation in a subset of AML patients.
T-Cell Receptor Beta Gene Rearrangement (TCRB)
PCR fragment analysis detecting clonal T-cell receptor beta rearrangements for T-cell malignancy diagnosis and monitoring. May be ordered concurrently with TCRG or as reflex.
KIT D816V Mutation Analysis
Allele-specific PCR detection of the KIT D816V mutation in core-binding factor AML and mastocytosis.
T-Cell Receptor Gamma Gene Rearrangement (TCRG)
PCR fragment analysis detecting clonal T-cell receptor gamma rearrangements for T-cell malignancy diagnosis and monitoring.
KMT2A::AFDN t(6;11) (aka KMT2A::MLLT4 or MLL::AF6)
Quantitative RQ-PCR detection of KMT2A::AFDN fusion transcripts from t(6;11) involving the 11q23 KMT2A locus.
TCF3::PBX1 (E2A::PBX1) t(1;19)
Quantitative RQ-PCR detection of TCF3::PBX1 (E2A::PBX1) fusion from t(1;19) for ALL diagnosis and minimal residual disease monitoring.
KMT2A::AFF1 t(4;11) (aka MLL::AF4)
Quantitative RQ-PCR detection of KMT2A::AFF1 fusion transcripts from t(4;11), associated with poor prognosis in B-ALL.