Test Name:
TCF3::PBX1 (E2A::PBX1) t(1;19)
CPT Code:
81401
Turn Around Time:
24 – 72 hours
Clinical Application:
Detection and quantitative monitoring of the TCF3::PBX1 fusion transcripts, which are the molecular result of the t(1;19) translocation and can be used for quantitative minimal residual disease monitoring in ALL
Diagnosis and monitoring.
Methodology:
Real-Time Quantitative PCR, minimum sensitivity: 0.0%
E2A exon 13 – PBX1 exon2
Specimen Requirements:
RNA-based assays
Peripheral Blood: Minimum 2 mL in EDTA (purple top) preferred or 2 mL in sodium heparin (green top)
Bone Marrow: Minimum 2 mL in EDTA (purple top) preferred or 2 mL in sodium heparin (green top)
Storage and Transportation:
Please store and ship specimens at ambient temperatures.
Ship RNA-based assays within 24 hours for optimal results.
Please refer to our full specimen requirements at Hematologics/Specimen Requirements for additional information and for directions on the storage and shipping of extracted DNA or RNA.