Test Name:
PML::RARA t(15;17)
CPT Code:
81315
Turn Around Time:
24 – 72 hours
Clinical Application:
Detection and quantitative monitoring of the PML::RARA fusion transcripts, the molecular result of the t(15;17) translocation, associated with the majority of acute promyelocytic leukemia (APL) cases.
Diagnosis and monitoring.
Methodology:
Real-Time Quantitative PCR, minimum sensitivity: 0.01%
Multiplex PCR test can detect all three possible PML:RARA isoforms, referred to as long (L, or bcr1), variant (V, or bcr2) and short (S, or BCR3)
STAT testing available upon request.
Specimen Requirements:
RNA-based assays
Peripheral Blood: Minimum 2 mL in EDTA (purple top) preferred or 2 mL in sodium heparin (green top)
Bone Marrow: Minimum 2 mL in EDTA (purple top) preferred or 2 mL in sodium heparin (green top)
Storage and Transportation:
Please store and ship specimens at ambient temperatures.
Ship RNA-based assays within 24 hours for optimal results.
Please refer to our full specimen requirements at Hematologics/Specimen Requirements for additional information and for directions on the storage and shipping of extracted DNA or RNA.