Test Name:
KMT2A::MLLT3 (MLL::AF9) t(9;11)
CPT Code:
81401
Turn Around Time:
24 – 72 hours
Clinical Application:
Detection and quantitative monitoring of the KMT2A::MLLT3 fusion transcripts, the molecular result of the t(9;11) translocation.
Diagnosis and monitoring.
Methodology:
Real-Time Quantitative PCR, minimum sensitivity: 0.01%
Multiplex PCR, detects three different variants: KMT2A exon 10 – MLLT3 exon 6; KMT2A exon 8 – MLLT3 exon 9, and KMT2A exon 8 – MLLT3 exon 10
Specimen Requirements:
RNA-based assays
Peripheral Blood: Minimum 2 mL in EDTA (purple top) preferred or 2 mL in sodium heparin (green top)
Bone Marrow: Minimum 2 mL in EDTA (purple top) preferred or 2 mL in sodium heparin (green top)
Storage and Transportation:
Please store and ship specimens at ambient temperatures.
Ship RNA-based assays within 24 hours for optimal results.
Please refer to our full specimen requirements at Hematologics/Specimen Requirements for additional information and for directions on the storage and shipping of extracted DNA or RNA.