Test Name:
FIP1L1::PDGFRA del(4q12)
CPT Code:
81314
Turn Around Time:
24 – 72 hours
Clinical Application:
Detection and quantitative monitoring of the interstitial deletion on chromosome 4q12 resulting in the FIP1L1::PDGFRA fusion gene. This fusion is correlated with hypereosinophilia syndrome (HES) and chronic eosinophilic leukemia (CEL). Diagnosis and monitoring.
Methodology:
Real-Time Quantitative PCR. Minimum sensitivity: 0.01%
Specimen Requirements:
RNA-based assays
Peripheral Blood: Minimum 2 mL in EDTA (purple top) preferred or 2 mL in sodium heparin (green top)
Bone Marrow: Minimum 2 mL in EDTA (purple top) preferred or 2 mL in sodium heparin (green top)
Storage and Transportation:
Please store and ship specimens at ambient temperatures.
Ship RNA-based assays within 24 hours for optimal results.
Please refer to our full specimen requirements at Hematologics/Specimen Requirements for additional information and for directions on the storage and shipping of extracted DNA or RNA.