Test Name:
PML::RARA t(15;17)
CPT Code:
81206 / 81207
Turn Around Time:
RQ-PCR 24 – 72 hours
Clinical Application:
Detection and quantitative monitoring of the t(9;22) BCR::ABL1 fusion transcript. This assay can detect two different types of BCR-ABL1 fusion transcripts associated with CML, ALL, and AML: e14a2 (previously b3a2) (major breakpoint, p210) and e1a2 (minor breakpoint, p190).
Diagnosis and monitoring.
Methodology:
Real-Time Quantitative PCR. Minimum sensitivity: 0.001%
Specimen Requirements:
DNA-based assays
Peripheral Blood: Minimum 2 mL in EDTA (purple top) preferred or 2 mL in sodium heparin (green top)
Bone Marrow: Minimum 2 mL in EDTA (purple top) preferred or 2 mL in sodium heparin (green top)
Storage and Transportation:
Please store and ship specimens at ambient temperatures.
Ship RNA-based assays within 24 hours for optimal results.
Please refer to our full specimen requirements at Hematologics/Specimen Requirements for additional information and for directions on the storage and shipping of extracted DNA or RNA.