CXCR4 Mutation Analysis
Sanger sequencing of CXCR4 c-terminal mutations associated with ibrutinib resistance in Waldenström's macroglobulinemia.
IDH1 Mutation Analysis
Sanger sequencing of IDH1 exon 4 mutations including R132 to inform IDH inhibitor treatment decisions.
T-Cell Receptor Gamma Gene Rearrangement (TCRG)
PCR fragment analysis detecting clonal T-cell receptor gamma rearrangements for T-cell malignancy diagnosis and monitoring.
IDH2 Mutation Analysis
Sanger sequencing of IDH2 exon 4 mutations at codons R140 and R172 to inform IDH inhibitor treatment decisions.
T-Cell Receptor Beta Gene Rearrangement (TCRB)
PCR fragment analysis detecting clonal T-cell receptor beta rearrangements for T-cell malignancy diagnosis and monitoring. May be ordered concurrently with TCRG or as reflex.
MYD88 L265P Mutation Analysis
Cell sorting and Sanger sequencing detection of MYD88 L265P mutation in lymphoplasmacytic lymphoma and Waldenström's macroglobulinemia.
FLT3 ITD/TKD Mutation Analysis
PCR fragment analysis with EcoRV digest detecting FLT3 internal tandem duplications (ITD) and D835 tyrosine kinase domain mutations in AML.
B-Cell IGK Gene Rearrangement
PCR fragment-length analysis of clonal IGK rearrangements for B-cell lymphoma diagnosis and minimal residual disease monitoring.
