T-Cell Receptor Gamma Gene Rearrangement (TCRG)
PCR fragment analysis detecting clonal T-cell receptor gamma rearrangements for T-cell malignancy diagnosis and monitoring.
KMT2A::AFDN t(6;11) (aka KMT2A::MLLT4 or MLL::AF6)
Quantitative RQ-PCR detection of KMT2A::AFDN fusion transcripts from t(6;11) involving the 11q23 KMT2A locus.
TCF3::PBX1 (E2A::PBX1) t(1;19)
Quantitative RQ-PCR detection of TCF3::PBX1 (E2A::PBX1) fusion from t(1;19) for ALL diagnosis and minimal residual disease monitoring.
KMT2A::AFF1 t(4;11) (aka MLL::AF4)
Quantitative RQ-PCR detection of KMT2A::AFF1 fusion transcripts from t(4;11), associated with poor prognosis in B-ALL.
KMT2A::MLLT10 (MLL::AF10) t(10;11)
Quantitative RQ-PCR detection of KMT2A::MLLT10 fusion transcripts from the t(10;11) translocation.
KMT2A::MLLT11 (MLL::AF1) t(1;11)
Quantitative RQ-PCR detection of KMT2A::MLLT11 fusion transcripts from the t(1;11) translocation.
KMT2A::MLLT3 (MLL::AF9) t(9;11)
Quantitative RQ-PCR detection of KMT2A::MLLT3 fusion transcripts from the t(9;11) translocation.
MYD88 L265P Mutation Analysis
Allele-specific PCR detection of MYD88 L265P mutation in lymphoplasmacytic lymphoma and Waldenström's macroglobulinemia.
KMT2A::MLLT1 / KMT2A::ELL t(11;19)
Quantitative RQ-PCR detection of KMT2A::MLLT1 (MLL::ENL) and KMT2A::ELL (MLL::ELL) fusion transcripts from t(11;19) in ALL and AML.
NPM1 Mutation Analysis
PCR fragment analysis of common 4 bp insertion mutations in NPM1 exon 12 for AML diagnosis.