JAK2 V617F Mutation Analysis
Allele-specific PCR detection of the JAK2 V617F mutation for myeloproliferative neoplasm diagnosis and monitoring.
T-Cell Receptor Gamma Gene Rearrangement (TCRG)
PCR fragment analysis detecting clonal T-cell receptor gamma rearrangements for T-cell malignancy diagnosis and monitoring.
KAT6A::CREBBP t(8;16)
Quantitative RQ-PCR detection of the KAT6A::CREBBP fusion from t(8;16)(p11;p13) translocation in a subset of AML patients.
TCF3::PBX1 (E2A::PBX1) t(1;19)
Quantitative RQ-PCR detection of TCF3::PBX1 (E2A::PBX1) fusion from t(1;19) for ALL diagnosis and minimal residual disease monitoring.
KIT D816V Mutation Analysis
Allele-specific PCR detection of the KIT D816V mutation in core-binding factor AML and mastocytosis.
KMT2A::AFDN t(6;11) (aka KMT2A::MLLT4 or MLL::AF6)
Quantitative RQ-PCR detection of KMT2A::AFDN fusion transcripts from t(6;11) involving the 11q23 KMT2A locus.
KMT2A::AFF1 t(4;11) (aka MLL::AF4)
Quantitative RQ-PCR detection of KMT2A::AFF1 fusion transcripts from t(4;11), associated with poor prognosis in B-ALL.
KMT2A::MLLT10 (MLL::AF10) t(10;11)
Quantitative RQ-PCR detection of KMT2A::MLLT10 fusion transcripts from the t(10;11) translocation.
KMT2A::MLLT11 (MLL::AF1) t(1;11)
Quantitative RQ-PCR detection of KMT2A::MLLT11 fusion transcripts from the t(1;11) translocation.
BRAF V600E Mutation Analysis
Sanger sequencing detection of the BRAF V600E mutation for hairy cell leukemia diagnosis and monitoring.