KIT D816V Mutation Analysis
Allele-specific PCR detection of the KIT D816V mutation in core-binding factor AML and mastocytosis.
KMT2A::AFDN t(6;11) (aka KMT2A::MLLT4 or MLL::AF6)
Quantitative RQ-PCR detection of KMT2A::AFDN fusion transcripts from t(6;11) involving the 11q23 KMT2A locus.
KMT2A::AFF1 t(4;11) (aka MLL::AF4)
Quantitative RQ-PCR detection of KMT2A::AFF1 fusion transcripts from t(4;11), associated with poor prognosis in B-ALL.
KMT2A::MLLT10 (MLL::AF10) t(10;11)
Quantitative RQ-PCR detection of KMT2A::MLLT10 fusion transcripts from the t(10;11) translocation.
KMT2A::MLLT11 (MLL::AF1) t(1;11)
Quantitative RQ-PCR detection of KMT2A::MLLT11 fusion transcripts from the t(1;11) translocation.
KMT2A::MLLT3 (MLL::AF9) t(9;11)
Quantitative RQ-PCR detection of KMT2A::MLLT3 fusion transcripts from the t(9;11) translocation.
MYD88 L265P Mutation Analysis
Allele-specific PCR detection of MYD88 L265P mutation in lymphoplasmacytic lymphoma and Waldenström's macroglobulinemia.
KMT2A::MLLT1 / KMT2A::ELL t(11;19)
Quantitative RQ-PCR detection of KMT2A::MLLT1 (MLL::ENL) and KMT2A::ELL (MLL::ELL) fusion transcripts from t(11;19) in ALL and AML.
NUP98::KDM5A t(11;12)
Quantitative RQ-PCR detection of NUP98::KDM5A fusion transcripts from the t(11;12)(p15;p13) translocation.
CEBPa bZIP Mutation Analysis
PCR fragment-length analysis of duplications/deletions in the CEBPA bZIP domain for AML diagnosis and monitoring.
