Diagnosis

CBFB::MYH11 inv(16) or t(16;16)

Quantitative RQ-PCR detection and monitoring of CBFB::MYH11 fusion transcripts (types A, D, E) from inv(16)/t(16;16) in AML.

CBFB::MYH11 inv(16) or t(16;16)Eric Johnson2026-05-03T16:03:03-07:00

CEBPa bZIP Mutation Analysis

PCR fragment-length analysis of duplications/deletions in the CEBPA bZIP domain for AML diagnosis and monitoring.

CEBPa bZIP Mutation AnalysisEric Johnson2026-05-03T16:03:03-07:00

CXCR4 Mutation Analysis

Sanger sequencing of CXCR4 c-terminal mutations associated with ibrutinib resistance in Waldenström's macroglobulinemia.

CXCR4 Mutation AnalysisEric Johnson2026-05-03T16:03:03-07:00

DEK::NUP214 t(6;9)

Quantitative RQ-PCR detection and monitoring of the t(6;9)(p22;q34) DEK::NUP214 fusion transcript in AML.

DEK::NUP214 t(6;9)Eric Johnson2026-05-03T16:03:03-07:00

ETV6::RUNX1 t(12;21)

Quantitative RQ-PCR detection of the t(12;21) ETV6::RUNX1 (TEL::AML1) fusion, associated with favorable prognosis in ALL.

ETV6::RUNX1 t(12;21)Eric Johnson2026-05-03T16:03:03-07:00

FIP1L1::PDGFRA del(4q12)

Quantitative RQ-PCR detection of the FIP1L1::PDGFRA fusion from interstitial 4q12 deletion in HES and chronic eosinophilic leukemia.

FIP1L1::PDGFRA del(4q12)Eric Johnson2026-05-03T16:03:03-07:00

FLT3 ITD/TKD Mutation Analysis

PCR fragment analysis with EcoRV digest detecting FLT3 internal tandem duplications (ITD) and D835 tyrosine kinase domain mutations in AML.

FLT3 ITD/TKD Mutation AnalysisEric Johnson2026-05-03T16:03:03-07:00

IDH1 Mutation Analysis

Sanger sequencing of IDH1 exon 4 mutations including R132 to inform IDH inhibitor treatment decisions.

IDH1 Mutation AnalysisEric Johnson2026-05-03T16:03:03-07:00

BCR::ABL1 IS t(9;22)

Quantitative RQ-PCR detection and monitoring of the t(9;22) BCR::ABL1 fusion transcript (p210 and p190) for CML, ALL, and AML diagnosis and MRD.

BCR::ABL1 IS t(9;22)Eric Johnson2026-05-03T15:05:35-07:00