NUP98::KDM5A t(11;12)
Quantitative RQ-PCR detection of NUP98::KDM5A fusion transcripts from the t(11;12)(p15;p13) translocation.
NUP98::NSD1 t(5;11)
Quantitative RQ-PCR detection of NUP98::NSD1 fusion transcripts from the cryptic t(5;11) translocation.
PML::RARA t(15;17)
Multiplex RQ-PCR detection of PML::RARA fusion transcripts (long, variant, short isoforms) for acute promyelocytic leukemia diagnosis and monitoring. STAT testing available.
RBM15::MRTFA t(1;22)
Quantitative RQ-PCR detection of RBM15::MRTFA (MKL1) fusion transcripts from the t(1;22) translocation.
RUNX1::RUNX1T1 (AML1-ETO) t(8;21)
Quantitative RQ-PCR detection of RUNX1::RUNX1T1 (AML1::ETO) fusion from t(8;21), associated with favorable prognosis in AML.
JAK2 V617F Mutation Analysis
Allele-specific PCR detection of the JAK2 V617F mutation for myeloproliferative neoplasm diagnosis and monitoring.
STAT3 Mutation Analysis
Sanger sequencing of STAT3 exons 19, 20, and 21 mutations for T-LGL leukemia diagnosis. Cell sorting available for increased sensitivity.
KAT6A::CREBBP t(8;16)
Quantitative RQ-PCR detection of the KAT6A::CREBBP fusion from t(8;16)(p11;p13) translocation in a subset of AML patients.
T-Cell Receptor Beta Gene Rearrangement (TCRB)
PCR fragment analysis detecting clonal T-cell receptor beta rearrangements for T-cell malignancy diagnosis and monitoring. May be ordered concurrently with TCRG or as reflex.
KIT D816V Mutation Analysis
Allele-specific PCR detection of the KIT D816V mutation in core-binding factor AML and mastocytosis.