JAK2 V617F Mutation Analysis
Allele-specific PCR detection of the JAK2 V617F mutation for myeloproliferative neoplasm diagnosis and monitoring.
STAT3 Mutation Analysis
Sanger sequencing of STAT3 exons 19, 20, and 21 mutations for T-LGL leukemia diagnosis. Cell sorting available for increased sensitivity.
CALR Mutation Analysis
PCR fragment-length analysis of CALR exon 9 insertion/deletion mutations for myeloproliferative neoplasm diagnosis and monitoring.
BCR::ABL1 IS t(9;22)
Quantitative RT-PCR detection and monitoring of the t(9;22) BCR::ABL1 fusion transcript (p210 and p190) for CML, ALL, and AML diagnosis and MRD.
BCR::ABL1 Qualitative Breakpoints p190 vs p210
Qualitative RT-PCR identification of BCR::ABL1 fusion transcript breakpoint type (major p210 vs minor p190) for diagnosis of CML, ALL, and AML.
KMT2A::MLLT11 (MLL::AF1) t(1;11)
Quantitative RT-PCR detection of KMT2A::MLLT11 fusion transcripts from the t(1;11) translocation.
CBFB::MYH11 inv(16) or t(16;16)
Quantitative RT-PCR detection and monitoring of CBFB::MYH11 fusion transcripts (types A, D, E) from inv(16)/t(16;16) in AML.
CBFA2T3::GLIS2
Quantitative RT-PCR detection and monitoring of the inv(16)(p13.3q24.3) CBFA2T3::GLIS2 fusion in AML with RAM immunophenotype.
KAT6A::CREBBP t(8;16)
Quantitative RT-PCR detection of the KAT6A::CREBBP fusion from t(8;16)(p11;p13) translocation in a subset of AML patients.
CEBPa bZIP Mutation Analysis
PCR fragment-length analysis of duplications/deletions in the CEBPA bZIP domain for AML diagnosis and monitoring.
