JAK2 V617F Mutation Analysis
Allele-specific PCR detection of the JAK2 V617F mutation for myeloproliferative neoplasm diagnosis and monitoring.
KIT D816V Mutation Analysis
Allele-specific PCR detection of the KIT D816V mutation in core-binding factor AML and mastocytosis.
MYD88 L265P Mutation Analysis
Allele-specific PCR detection of MYD88 L265P mutation in lymphoplasmacytic lymphoma and Waldenström's macroglobulinemia.
NPM1 Mutation Analysis
PCR fragment analysis of common 4 bp insertion mutations in NPM1 exon 12 for AML diagnosis.
STAT3 Mutation Analysis
Sanger sequencing of STAT3 exons 19, 20, and 21 mutations for T-LGL leukemia diagnosis. Cell sorting available for increased sensitivity.
T-Cell Receptor Beta Gene Rearrangement (TCRB)
PCR fragment analysis detecting clonal T-cell receptor beta rearrangements for T-cell malignancy diagnosis and monitoring. May be ordered concurrently with TCRG or as reflex.
T-Cell Receptor Gamma Gene Rearrangement (TCRG)
PCR fragment analysis detecting clonal T-cell receptor gamma rearrangements for T-cell malignancy diagnosis and monitoring.
CXCR4 Mutation Analysis
Sanger sequencing of CXCR4 c-terminal mutations associated with ibrutinib resistance in Waldenström's macroglobulinemia.
FLT3 ITD/TKD Mutation Analysis
PCR fragment analysis with EcoRV digest detecting FLT3 internal tandem duplications (ITD) and D835 tyrosine kinase domain mutations in AML.
IDH1 Mutation Analysis
Sanger sequencing of IDH1 exon 4 mutations including R132 to inform IDH inhibitor treatment decisions.