Services

Our own state-of-the-art flow cytometric, cytogenetic, and molecular analysis laboratories provide a comprehensive test menu for immunophenotyping, karyotyping and FISH studies, gene rearrangement, chromosomal translocation and point mutation studies.

Interpretative reports are generated and reviewed by both Drs. Denise A. Wells and Michael R. Loken. Clinical information (patient history, surgical, and/or pathological diagnoses) is essential for workup and evaluation of specimens. Unexpected results clinically significant to patient care are telephoned or e-mailed to the ordering physician or laboratory. Reports are faxed to the client as they are generated usually within 24-48 hours of receipt of specimen. Final (hard copy) reports are mailed to the client.

Flow Cytometry

1) Immunophenotyping of Peripheral Blood and Bone Marrow Aspirate Specimens

2) Immunophenotyping of Tissue Specimens

3) Cell Sorting: Tumor Cell Confirmation, Lineage Specific Chimerism, Monoclonality Profiling

4) Immunocompetancy / Lymphocyte Subset Analysis

5) Quantitative Progenitor Cell (CD34) Analysi

Molecular Analysis

1) Molecular Diagnostic Test Menu

2) B- and T-cell gene rearrangements PCR

3) Quantitative RQ-PCR assays

4) Activating Point Mutation Assays

5) Microsatellite Instabipty (MSI)

6) CLL IGHV Mutation Analysis

7) Retrospect™ DNA Archiving Service

Disease Applications

• Myelodysplastic Syndrome (MDS)/ Myelopropferative Disorders (MPD)

• Non-Hodgkins Lymphoma

• Myeloma

• Chronic Myelogenous Leukemia (CML)

• Acute Leukemia

• Paroxysmal Nocturnal Hemoglobinuria

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