Hematologics Inc.

References

  1. Loken MR, Terstappen LWMM, Civin CI, Fackler, MJ: Flow cytometric characterization of erythroid. lymphoid and monomyeloid lineages in normal human bone marrow. In Flow Cytometry in Hematology. Laerum OD, Bjerksnes R. eds. Academic Press, New York, pp 31-42, 1992.
    -see pdf file.

  2. Civin CI, Loken MR: Cell Surface Antigens on Human Marrow Cells: Dissection of Hematopoietic Development Using Monoclonal Antibodies and Multiparameter Flow cytometry. in "Concise Reviews in Clinical and Experimental Hematology" Martin J. Murphy ed. AlphaMed Press, Dayton OH, 1992, pp 149-159.
    -see pdf file.

  3. Terstappen LWMM, Hollander Z, Meiners H, Loken MR: Quantitative Comparison of myeloid antigens; on five lineages of mature peripheral blood cells. J Leuk Biol 48:138-148, 1990.
    -see pdf file.

  4. Loken MR, Lanier LL: Three color immunofluorescence of Leu antigens on human peripheral blood using two lasers on a fluorescence activated cell sorter. Cytometry. 5:151-158 (1984).
    -see pdf file.

  5. Hollander Z, Shah VO, Civin CI, Loken MR. Assessment of proliferation during maturation of the B lymphoid lineage in normal human bone marrow. Blood. 1988 Feb;71(2):528-31.
    -see pdf file.

  6. Loken MR, Civin CI, Bigbee WL, Langlois RG, Jensen RH. Coordinate glycosylation and cell surface expression of glycophorin A during normal human erythropoiesis. Blood. 1987 Dec;70(6):1959-61.
    -see pdf file.

  7. Loken MR, Shah VO, Dattilio KL, Civin CI. Flow cytometric analysis of human bone marrow: I. Normal erythroid development. Blood. 1987 Jan;69(1):255-63.
    -see pdf file.

  8. Loken MR, Shah VO, Dattilio KL, Civin CI. Flow cytometric analysis of human bone marrow. II. Normal B lymphocyte development. Blood. 1987 Nov;70(5):1316-24.
    -see pdf file.

  9. Terstappen LWMM, Shah VO, Civin CI, Hurwitz CA, Loken MR: Multidimensional flow cytometry as a new approach for discrimination between normal and leukemic cells in peripheral blood and bone marrow. in "Progress in Cytometry II Flow and Image" A Jansen ed. Becton Dickinson, Erembodegem, Belgium, 1989, pp 4-29.
    -see pdf file.

  10. Terstappen LWMM, Konemann S, Safford M, Loken MR, Zurlutter K, Buchner Th, Hiddemann W, Wormann B: Flow cytometric characterization of Acute Myeloid Leukemia. Part II. Phenotypic heterogeneity at diagnosis. Leukemia, 6: 70-80, 1991.
    -see pdf file.

  11. Terstappen LW, Konemann S, Safford M, Loken MR, Zurlutter K, Buchner T, Hiddemann W, Wormann B. Flow cytometric characterization of acute myeloid leukemia. Part 1. Significance of light scattering properties. Leukemia. 1991 Apr;5(4):315-21.
    -see pdf file.

  12. LeBien TW, Wormann B, Villablanca JG, Law CL, Steinberg LM, Shah VO, Loken MR. Multiparameter flow cytometric analysis of human fetal bone marrow B cells. Leukemia. 1990 May;4(5):354-8.
    -see pdf file.

  13. Hurwitz CA, Loken MR, Graham ML, Karp JE, Borowitz MJ, Pullen DJ, Civin CI. Asynchronous antigen expression in B lineage acute lymphoblastic leukemia. Blood. 1988 Jul;72(1):299-307.
    -see pdf file.

  14. Stelzer GT, Shults KE, Wormsley SB, Loken MR: Detection of occult lymphoma cells in bone marrow aspirates by multi-dimensional flow cytometry. in Prog. Clin. Biol. Res. 337: 629-634, 1992.
    -see pdf file.

  15. Sievers EL, Loken MR: Detection of minimal residual disease in acute myelogenous leukemia. J. Ped Hem/Onc 17:123-133, 1995.
    -see pdf file.

  16. Larson RA, Boogaerts M, Estey E, Karanes C, Stadtmauer EA, Sievers EL, Mineur P, Bennett JM, Berger MS, Eten CB, Munteanu M, Loken MR, Van Dongen JJ, Bernstein ID, Appelbaum FR; Mylotarg Study Group. Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin). Leukemia. 2002 Sep;16(9):1627-36.
    -see pdf file.

  17. Meshinchi S, Thomson B, Finn LS, Leisenring W, Green C, Radich JP, Loken M, Hawkins D.Comparison of multidimensional flow cytometry with standard morphology for evaluation of early marrow response in pediatric acute lymphoblastic leukemia. J Pediatr Hematol Oncol. 2001 Dec;23(9):585-90.
    -see pdf file.

  18. Sievers EL, Larson RA, Stadtmauer EA, Estey E, Lowenberg B, Dombret H, Karanes C, Theobald M, Bennett JM, Sherman ML, Berger MS, Eten CB, Loken MR, van Dongen JJ, Bernstein ID, Appelbaum FR; Mylotarg Study Group. Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse. J Clin Oncol. 2001 Jul 1;19(13):3244-54.
    -see pdf file.

  19. Cooper LJ, Shannon KM, Loken MR, Weaver M, Stephens K, Sievers EL.Evidence that juvenile myelomonocytic leukemia can arise from a pluripotential stem cell.Blood. 2000 Sep 15;96(6):2310-3.
    -see pdf file.

  20. Mielcarek M, Bryant E, Loken M, Torok-Storb B, Storb R. Haemopoietic reconstitution by donor-derived myelodysplastic progenitor cells after haemopoietic stem cell transplantation. Br J Haematol. 1999 May;105(2):361-5.
    -see pdf file.

  21. Rowley SD, Loken M, Radich J, Kunkle LA, Mills BJ, Gooley T, Holmberg L, McSweeney P, Beach K, MacLeod B, Appelbaum F, Bensinger WI. Isolation of CD34+ cells from blood stem cell components using the Baxter Isolex system. Bone Marrow Transplant. 1998 Jun;21(12):1253-62.
    -see pdf file.

  22. Sheckler VL, Loken MR. Routine quantitation of white cells as low as 0.001 per microL in platelet components. Transfusion. 1993 Mar;33(3):256-61.
    -see pdf file.

  23. Sievers EL, Lange BJ, Alonzo TA, Gerbing RB, Bernstein ID, Smith FO, Arceci RJ, Woods WG, Loken MR. Immunophenotypic evidence of leukemia after induction therapy predicts relapse: results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia. Blood. 2003 May 1;101(9):3398-406.
    -see pdf file.

  24. Wells DA, Benesch M, Loken MR,Vallejo C, Myerson D, Leisenring WM, Deeg HJ. Myeloid and monocytic dyspoiesis as determined by flow cytometric scoring in myelodysplastic syndrome correlates with the IPSS and with outcome after hemopoietic stem cell transplantation. Blood, 1 July 2003, vol. 102, 1, 394-403.
    -see pdf file.

  25. Storek, J; Wells, D; Dawson, M; Storer, B; Maloney, D. Factors influencing B-lymphopoiesis after allogeneic hematopoietic cell transplantation. Blood, vol. 98, 2, 489-491, 2001.
    -see pdf file.

  26. Loken, MR; Rowley, S; McSweeney, P, Wells, DA. Quantification of lymphoma in CD34+ enriched stem cell harvests: Evidence of non random, non specific contamination. Cancer Research Therapy and Control, vol. 11, pp.33-39, 2001.
    -see pdf file.

  27. Shulman, H. M.; Wells, D.; Gooley, T.; Myerson, D.; Bryant, E.; Loken, M. R. The biologic significance of rare peripheral blasts after hematopoietic cell transplantation is predicted by multidimensional flow cytometry. Am J Clin Pathol, 112, 4, 513-23, 2000.
    -see pdf file.

  28. Wells DA, Hall MC, Shulman HM, Loken MR. Occult B cell malignancies can be detected by three-color flow cytometry in patients with cytopenias. Leukemia 1998;12(12):2015-23.
    -see pdf file.

  29. Wells DA, Sale GE, Shulman HM, Myerson D, Bryant EM, Gooley T, and Loken MR. Multidimensional flow cytometry of marrow can differentiate leukemic lymphoblasts from normal lymphoblasts and myeloblasts following chemotherapy and/or bone marrow transplant. Am J Clin Path 110, 84-94, 1998.
    -see pdf file.

  30. McSweeney P, Wells D, Shults K, Nash R, and Loken M. Tumor-specific aneuploidy not detected in CD19-positive B-lymphoid cells from myeloma patients in a multidimensional flow cytometric analysis. Blood, vol 88, July 15, 1996, pp 622-632.
    -see pdf file.

  31. Terstappen LWMM, Johnsen S, Segers-Nolten I, Loken MR: Identification and characterization of plasma cells in normal human bone marrow by high resolution flow cytometry. Blood, 76:1739-1747, 1990.
    -see pdf file.

  32. Harris NA et al. A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group. Blood 84:1361-1392 (1994).

  33. Owens M, Loken MR: Flow Cytometry Principles for Clinical Laboratory Practice: Quality Assurance for Quantitative Immunophenotyping. Wylie-Liss, New York, 1995.
    see link to relevant text.

  34. Loken MR, Civin CI: Laboratory Assessment of Lymphohematopoietic Progenitor and Stem Cells, in Peripheral Blood Stem Cells, Smith, DM. and Sacher RA eds, Amer. Assoc. Blood Banks, Bethesda, 1993, pp 19-29.
    -see pdf file.

  35. Zehentner BK, Fritschle W, Stelzer T, Ghirardelli KM, Hunter K, Wentzel C, Bennington R, Hansen CL, Myerson D, Kalnoski M, Wells DA, Loken MR: Minimal Disease Detection and Confirmation in Hematologic Malignancies: Combining Cell Sorting with Clonality Profiling, Clinical Chemistry 52:3 pp430-437, 2006.
    pdf -see pdf file.

  36. Valent, et al: Definitions and Standards in the Diagnosis and Treatment of The Myelodysplastic Syndromes: Consensus Statements and Report from a Working Conference
    -see pdf file.