Hematologics, Inc., a diagnostic service laboratory established in 1995, is built on a long history of research. Its principals and staff, who have decades of training and experience, invented many of the techniques that are now standard in the field:

• Over 30 years experience in flow cytometry, starting with the first FACS instrument at Stanford in 1973
• Invented multi-color immunofluorescence and multi-angle light scatter
• Described the antigenic patterns expressed during normal hematopoietic cell development and defined both lineage and maturation of cells in erythroid, myeloid and lymphoid lineages
• Identified human progenitor cells and the hematopoietic stem cell
• Developed correction for blood contamination of bone marrow specimens
• Developed techniques, including CD45 vs. SSC (right angle light scatter) gating for separation of distinct populations in bone marrow
• Showed that tumors express normal antigens in abnormal relationships, allowing the detection of residual leukemia based on “difference from normal”
• Developed and fine tuned techniques for minimal disease detection even in the absence of a diagnostic specimen
• Advanced the use of flow cytometry for diagnosis and determination of prognostic outcome in MDS
• Pioneered the use of cell sorting in confirmation of minimal residual disease

Hematologics, Inc. combines unique expertise in multi-dimensional flow cytometry, tumor cell sorting, cytogenetics and molecular genetics with a broad understanding of hematopoiesis and clinical knowledge to provide you with the information you need. Our Retrospect DNA ArchivingTM service offers yet one more approach for monitoring your patient for residual disease and determination of relapse.